CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 85 enrolled
Drug / intervention
Fecal microbiota transplantother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05998213
NCT05998213Phase 2Completed
CompareCT.gov

Transfer of Feces in Ulcerative Colitis 2; Improving Efficacy

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)·interventional·Posted Aug 18, 2023·Updated Mar 20, 2026

In Brief

A Phase 2 clinical trial evaluating Fecal microbiota transplant for Ulcerative Colitis and 2 related conditions. Completed, enrolled 85 participants across 1 site.

Detailed Summary

The goal of this placebo-controlled randomised multicenter trial is to evaluate the efficacy and safety of anaerobic prepared donor fecal microbiota transplantation (FMT) compared to autologous FMT in patient with ulcerative colitis. Participants will receive 4 treatments with frozen FMT via both upper and lower gastro-intestinal route (infusion via duodenal tube and enemas). Donors are selected based on microbiota profile.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsUlcerative Colitis, Ulcerative Colitis Flare, Ulcerative Colitis Acute
CountriesNetherlands
CollaboratorsUniversity Medical Center Groningen, UMC Utrecht

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedAug 18, 2023
Enrollment StartJun 12, 2020
Primary CompletionJan 10, 2025
Study CompletionDec 18, 2025
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 2.9 years ago

Interventions

Fecal microbiota transplantother

Frozen FMT via duodenal tube (2 times) and enemas (4 times)