CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 52 enrolled
Drug / intervention
0 ppm F (placebo, negative control) +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06010732
NCT06010732Phase 3Completed
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Comparison of the Remineralization Potential of an Optimized Fluoride Dentifrice With a Control Fluoride Dentifrice Using an in Situ Caries Model

Indiana University·interventional·Posted Aug 25, 2023·Updated Jun 15, 2025

In Brief

A Phase 3 clinical trial evaluating 0 ppm F (placebo, negative control), 1100 ppm F as sodium fluoride (positive control), and 1 other intervention for Caries. Completed, enrolled 52 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the remineralization potential of an optimized fluoride dentifrice to a control fluoride dentifrice in an in situ caries model.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCaries
CountriesUnited States
CollaboratorsHALEON

Timeline

Phase 3CompletedFinished
202420252026
First PostedAug 25, 2023
Enrollment StartOct 2, 2023
Primary CompletionFeb 22, 2024
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 2.9 years ago

Interventions

0 ppm F (placebo, negative control)drug

• Each subject will use this product during one of the three treatment periods in the crossover study design.

1100 ppm F as sodium fluoride (positive control)drug

• Each subject will use this product during one of the three treatment periods in the crossover study design.

1100 ppm F as sodium fluoride Test Productdrug

• Each subject will use this product during one of the three treatment periods in the crossover study design.