CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 16 enrolled
Drug / intervention
Bempedoic Acid 180 MG Oral Tablet +1 moredrug
Likely dose
Bempedoic Acid 180 MG Oral Tabletfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06021951
NCT06021951Phase 4Completed

An Open-Label Postmarking Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid and Ezetimibe in the Breast Milk of Healthy Lactating Women Administered Therapeutic Doses of Bempedoic Acid or Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP)

Esperion Therapeutics, Inc.·interventional·Posted Sep 1, 2023·Updated Apr 11, 2025

In Brief

A Phase 4 clinical trial evaluating Bempedoic Acid 180 MG Oral Tablet and Bempedoic Acid/Ezetimibe 180 MG-10 MG Oral Tablet for Healthy Lactating Women. Completed, enrolled 16 participants across 1 site.

Detailed Summary

This study is designed to characterize the excretion of bempedoic acid or bempedoic acid and ezetimibe into mature breast milk of healthy lactating women and assess the exposure to the breast fed infant by estimating the daily infant dosage and the relative infant dose (RID) of bempedoic acid or bempedoic acid and ezetimibe in breast milk after 6 consecutive daily doses of bempedoic acid or bempedoic acid/ezetimibe FCDP.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
202420252026
First PostedSep 1, 2023
Enrollment StartAug 4, 2023
Primary CompletionFeb 21, 2024
Study CompletionMar 22, 2024
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 2.8 years ago

Interventions

Bempedoic Acid 180 MG Oral Tabletdrug

Bempedoic Acid 180 MG Oral Tablet \[Nexletol\]

Bempedoic Acid/Ezetimibe 180 MG-10 MG Oral Tabletdrug

Bempedoic Acid/Ezetimibe 180 MG-10 MG Oral Tablet \[NEXLIZET\]