CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 2,000 enrolled
Drug / intervention
GSK's liquid oral live attenuated HRV +1 morecombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06025695
NCT06025695Phase 3Completed

A Phase III, Observer-blind, Randomized, Multicenter Study to Evaluate Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Rotarix Porcine Circovirus (PCV)-Free Liquid as Compared to GSK's Rotarix Liquid, Given in 2-doses in Healthy Chinese Infants Starting at Age 6-16 Weeks

GlaxoSmithKline·interventional·Posted Sep 6, 2023·Updated May 9, 2025

In Brief

A Phase 3 clinical trial evaluating GSK's liquid oral live attenuated HRV and PCV-free liquid formulation of GSK's oral live attenuated HRV for Gastroenteritis. Completed, enrolled 2,000 participants across 12 sites.

Detailed Summary

The purpose of this study is to evaluate the immunogenicity, reactogenicity and safety of the Porcine circovirus (PCV)-free liquid formulation of GlaxoSmithKline Biologicals' SA (GSK) oral live attenuated human rotavirus (HRV) study intervention compared to GSK's liquid oral live attenuated HRV study intervention in healthy Chinese infants 6 to 16 weeks of age at the time of the first study intervention administration.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGastroenteritis
CountriesChina
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedSep 6, 2023
Enrollment StartSep 1, 2023
Primary CompletionMay 28, 2024
Study CompletionOct 23, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 2.8 years ago

Interventions

GSK's liquid oral live attenuated HRVcombination

2 doses of GSK's liquid oral live attenuated HRV study intervention administered orally at Day 1 and Month 1, according to the immunization schedule for HRV study intervention licensed outside of China.

PCV-free liquid formulation of GSK's oral live attenuated HRVcombination

2 doses of PCV-free liquid formulation of GSK's oral live attenuated HRV study intervention administered orally at Day 1 and Month 1, according to the immunization schedule for HRV study intervention licensed outside of China.