CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 558 enrolled
Drug / intervention
Machine learning algorithmother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06029452
NCT06029452N/ACompleted

A Retrospective Chart Validation Study Evaluating the Performance of Machine Learning Algorithm (ML) to Predict the Clinical Diagnosis of Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt-CM) and Non-amyloid Heart Failure Among Patients With Heart Failure (HF)

Pfizer·observational·Posted Sep 8, 2023·Updated Jan 3, 2025

In Brief

An observational study evaluating Machine learning algorithm for ATTR-CM. Completed, enrolled 558 participants across 1 site.

Detailed Summary

This is an observational, retrospective non-inferiority study with a study sample from a large national database. A machine learning (ML) model will use a national database to predict the clinical diagnosis of ATTRwt-CM among HF patients. This study will include HF patients ≥50 years old.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsATTR-CM
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedSep 8, 2023
Enrollment StartSep 1, 2023
Primary CompletionNov 14, 2023
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 2.8 years ago

Interventions

Machine learning algorithmother

Software to calculate the predicted probability of ATTRwt-CM for these heart failure patients based on the presence and absence of certain features