CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 242 enrolled
Drug / intervention
Semaglutide +1 moredrug
Likely dose
Semaglutide 2.4 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06041217
NCT06041217Phase 3Completed

Efficacy and Safety of Semaglutide 2.4 mg Once-weekly in Adults With Overweight and Obesity

Novo Nordisk A/S·interventional·Posted Sep 18, 2023·Updated May 18, 2026

In Brief

A Phase 3 clinical trial evaluating Semaglutide and Placebo for Overweight and Obesity. Completed, enrolled 242 participants across 21 sites in 2 countries.

Detailed Summary

This study will look at how the investigational dose of semaglutide works in helping people with excess body weight, to lose weight. This study will compare the weight loss in people taking semaglutide to people taking "dummy" medicine (placebo). The study will last for about 1 year. The participants will have 12 visits at the clinic and 3 remote visits by phone calls with the study doctor or staff.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOverweight, Obesity
CountriesChina, Taiwan
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedSep 18, 2023
Enrollment StartSep 15, 2023
Primary CompletionApr 2, 2025
Study CompletionMay 7, 2025
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 2.8 years ago

Interventions

Semaglutidedrug

Subcutaneous injections of semaglutide once-weekly at escalating doses every fourth week until maintenance dose of 2.4 mg of semaglutide is reached.

Placebodrug

Subcutaneous injections of placebo once-weekly at escalation doses manner as semaglutide every fourth week until maintenance dose of placebo matched to 2.4 mg is reached.