CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 200 enrolled
Drug / intervention
SGLT2 inhibitor, GLP-1 RA +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06046560
NCT06046560Phase 4Completed

DRIVE Program: Diabetes Remote Intervention to improVe Use of Evidence-based Medications

Brigham and Women's Hospital·interventional·Posted Sep 21, 2023·Updated Oct 23, 2024

In Brief

A Phase 4 clinical trial evaluating SGLT2 inhibitor, GLP-1 RA and Education-First for Cardiovascular Diseases and Diabetes. Completed, enrolled 200 participants across 1 site.

Detailed Summary

A randomized remote, implementation trial in the Mass General Brigham network was performed on 200 patients with T2D at high CV or kidney risk. The study's primary objective was to create a remote diabetes management platform that improved the initiation and adherence to glucose-lowering medications with CV and kidney benefit and was evaluated by the primary outcome: increasing the proportion of patients with prescriptions for GDMT therapy by 6 months.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsNovo Nordisk A/S

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedSep 21, 2023
Enrollment StartMar 22, 2021
Primary CompletionJul 25, 2023
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 2.8 years ago

Interventions

SGLT2 inhibitor, GLP-1 RAdrug

Immediate initiation of guideline-directed medical therapy. Will also immediately receive the same educational services provided in the "Education-First" intervention.

Education-Firstbehavioral

For the first 2-months of their participation, patients in this arm will receive curated patient education, an alert to providers, provider education, and then after 2 months, be invited to participate in the remote clinic. The patient education would consist of curated video content and informational worksheets provided by email or secure patient messaging. Provider alerts would happen through notifying of a patient's eligibility for therapy.