CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 178 enrolled
Drug / intervention
Holmium laser with pulse modulation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06070714
NCT06070714N/ACompleted

Multi-Center Randomized Clinical Trial Evaluating the Efficiency and Safety of Holmium Laser With Moses Technology Versus SuperPulsed Laser System With Thulium Fiber Laser on Renal Stones

University of Wisconsin, Madison·interventional·Posted Oct 6, 2023·Updated Feb 27, 2026

In Brief

A clinical study evaluating Holmium laser with pulse modulation and Thulium fiber laser for Renal Stone. Completed, enrolled 178 participants across 4 sites.

Detailed Summary

This is a prospective randomized controlled trial designed to assess the efficacy and safety of Lumenis® Pulse™ P120H holmium laser system with the Moses technology (holmium laser with pulse modulation) versus the Soltive™ SuperPulsed Laser System with the thulium fiber laser (thulium fiber laser), in dusting of renal stones during ureteroscopy with laser lithotripsy. 310 participants will be enrolled across 5 research sites.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRenal Stone
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedOct 6, 2023
Enrollment StartSep 7, 2023
Primary CompletionOct 31, 2025
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 2.7 years ago

Interventions

Holmium laser with pulse modulationdevice

The holmium laser with pulse modulation emits two separate laser pulses with a short time interval between them. The first pulse divides the water between the laser fiber tip and the stone and the second pulse hits the stone unobstructed.

Thulium fiber laserdevice

The thulium fiber laser has a different wavelength then the holmium laser with pulse modulation and thus has slightly different energy properties. It has also been shown to increase ablative volume and decrease retropulsion without any safety concerns.