CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 18 enrolled
Drug / intervention
Zinc oxide nanoparticle coated orthodontic molar tubes (experimental) +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06089720
NCT06089720N/ACompleted

An Antimicrobial Effect of ZnO Nanoparticles Coated Orthodontic Molar Tube (A Randomized Clinical Trial)

University of Baghdad·interventional·Posted Oct 18, 2023·Updated Oct 18, 2023

In Brief

A clinical study evaluating Zinc oxide nanoparticle coated orthodontic molar tubes (experimental) and orthodontic molar tubes (control) for Evaluations, Diagnostic Self and 6 related conditions. Completed, enrolled 18 participants across 1 site.

Detailed Summary

Orthodontic treatment is an elective procedure to improve the patient's dentofacial appearance. The complex design of fixed appliances provides a platform that leads to increased plaque accumulation around orthodontic brackets. So, the risk to develop demineralization area adjacent to orthodontic brackets is a major barrier in achieving this goal. Oral hygiene is greatly complicated following the placement of fixed orthodontic Appliances. Molar tube in place are considered for nearly all patients experiencing fixed orthodontic therapy over the whole treatment period, which normally lasts 1.5 to 2 years. To the best of the authors' knowledge, the application and antimicrobial efficacy of zinc oxide (ZnO) nanoparticles coating on orthodontic molar tube material has not been integrated clinically. White spot lesions during orthodontic treatment have a documented etiology. Briefly, the accumulation of plaque and food around brackets, bands, wires, and other attachments caused decreased pH and increased S. mutans colonization, which led to the possibility of clinical demineralization. The aims of study are to assess the antimicrobial effect of nanoparticle coated stainless steel orthodontic molar tube material (OMT) with zinc oxide (ZnO) nanoparticles in relative to uncoated orthodontic molar tube (UOMT) against the streptococcus. mutans\& lactobacllius bacteria that cause white spot lesion around the fixed orthodontic appliance. .

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIraq
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedOct 18, 2023
Enrollment StartFeb 15, 2023
Primary CompletionSep 30, 2023
Study CompletionOct 4, 2023
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 2.7 years ago

Interventions

Zinc oxide nanoparticle coated orthodontic molar tubes (experimental)device

nine orthodontic patients each one will receive 2 coated zinc oxide nanoparticle molar tubes in split-mouth manner and will assess for antimicrobial effect on s. mutans \& lactobacillus after two weeks, in addition to evaluation of bond failure rate after three months.

orthodontic molar tubes (control)device

nine orthodontic patients each one will receive two uncoated molar tubes in split-mouth manner and will assess for antimicrobial effect on S. mutans \& lactobacillus after two weeks, also, evaluation of the bond failure rate after three months period.