CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 384 enrolled
Drug / intervention
Sweeping of membranesprocedure
Likely dose
Not stated in record
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Search/NCT06103071
NCT06103071N/ACompleted

Effectiveness of Membrane Sweeping on Successful Initiation of Labor and Subsequent Vaginal Birth in Patients With Previous One Cesarean Section.

HITEC-Institute of Medical Sciences·interventional·Posted Oct 26, 2023·Updated Mar 13, 2026

In Brief

A clinical study evaluating Sweeping of membranes for Vaginal Birth After Cesarean Section. Completed, enrolled 384 participants across 1 site.

Detailed Summary

In Pakistan rate of child birth through cesarean section increased from 3.2% in 1992 to 22% in 2018 .Due to increasing rates of cesarean sections and associated morbidity the investigators should focus to reduce rate of primary cesarean section as well as repeat cesarean with cephalic presentation and singleton pregnancy after previous 1 cesarean section. Therefore, all ladies who underwent previous 1 cesarean section for non-recurrent cause should be considered for vaginal birth. Though studies show that membrane sweeping does promote the onset of labor and avoid need for formal induction of labor for prolonged pregnancy but the effects of membrane sweeping in women with a prior cesarean delivery are largely unknown. This is a randomized controlled trial. Objective of the study was to determine the effect of membrane sweeping on the onset of labor, success of vaginal delivery and neonatal outcome in patients with previous one cesarean section.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPakistan
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedOct 26, 2023
Enrollment StartJan 15, 2023
Primary CompletionJul 10, 2024
Study CompletionJul 15, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 2.7 years ago

Interventions

Sweeping of membranesprocedure

After informed consent all the patients in interventional group will have sweeping of membranes from 37 weeks of pregnancy . It will be repeated weekly till 40 weeks.