CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 87 enrolled
Drug / intervention
Placebo +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06103188
NCT06103188Phase 3Completed

Comparing Melatonin to Diazepam as a Premedication: a Triple-blind, Randomized, Placebo Controlled Clinical Trial

University of Jordan·interventional·Posted Oct 26, 2023·Updated Jan 24, 2025

In Brief

A Phase 3 clinical trial evaluating Placebo, Diazepam, and 1 other intervention for Anxiety and Preoperative Anxiety. Completed, enrolled 87 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to compare the effect of melatonin, diazepam, and placebo on the level of anxiety in patients undergoing surgery. The main question it aims to answer is: • Is melatonin effective in reducing the anxiety of patients undergoing surgery? Participants will be asked to answer a questionnaire then they will receive either melatonin, diazepam, or placebo, and then after an hour, they will answer the same questionnaire again. Researchers will compare melatonin, diazepam, and placebo to see if melatonin is as effective in reducing the level of anxiety as diazepam in patients undergoing surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJordan
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedOct 26, 2023
Enrollment StartOct 2, 2023
Primary CompletionOct 30, 2023
TodayJul 2, 2026
Enrollment to primary: 28 daysPosted 2.7 years ago

Interventions

Placebodrug

The placebo pill will be given to the patients 1 hour prior to their planned surgery.

Diazepamdrug

Diazepam will be given to the patients 1 hour prior to their planned surgery.

Melatonindrug

Melatonin will be given to the patients 1 hour prior to their planned surgery.