CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Continuous Glucose Monitoring (CGM)-based titration algorithm implemented in DiAsdevice
Likely dose
Not stated in record
Key inclusion· 5
  • Age ≥18 years
  • Type 2 Diabetes diagnosed ≥180 days before screening
  • HbA1c 7-9% at screening
  • On daily basal insulin for ≥90 days
Key exclusion· 8
  • Hypersensitivity to Degludec
  • Current use of an insulin pump
  • Current use of short-acting insulin
  • Participation in another trial within 90 days of screening

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06111508
NCT06111508N/ACompleted

An Exploratory 16-Week Pilot Study of the Effect and Safety of a Novel CGM-Based Titration Algorithm for Basal Insulin, With or Without Non-Insulin Antidiabetic Drugs, in Type 2 Diabetes Mellitus Participants Treated With Basal Insulin.

University of Virginia·interventional·Posted Nov 1, 2023·Updated Mar 4, 2026

In Brief

A clinical study evaluating Continuous Glucose Monitoring (CGM)-based titration algorithm implemented in DiAs for Type 2 Diabetes. Completed, enrolled 30 participants across 2 sites.

Detailed Summary

The goal of this clinical trial is to compare the effect of a continuous glucose monitor (CGM) based titration algorithm to standard titration by self-monitoring blood glucose (SMBG) in participants with Type 2 Diabetes already using long acting insulin. The comparison aims to study the difference in glycemic control between the two therapies. Participants will be followed for 18 weeks and will be provided with Degludec insulin, insulin pen, and a CGM (Dexcom G6).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes
CountriesUnited States
CollaboratorsNovo Nordisk A/S

Timeline

N/ACompletedFinished
202420252026
First PostedNov 1, 2023
Enrollment StartNov 29, 2023
Primary CompletionSep 13, 2024
Study CompletionSep 16, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 2.7 years ago

Interventions

Continuous Glucose Monitoring (CGM)-based titration algorithm implemented in DiAsdevice

A Continuous Glucose Monitoring (CGM)-based once weekly titration algorithm of basal insulin as implemented in DiAs Cloud platform