CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 21 enrolled
Drug / intervention
biopsyother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06132386
NCT06132386N/ACompleted
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Analysis of Cellular Kinases and Aging in PBMCs and Colorectal Tissue

Johns Hopkins University·observational·Posted Nov 15, 2023·Updated Dec 24, 2025

In Brief

An observational study evaluating biopsy for HIV Infections and Aging. Completed, enrolled 21 participants across 1 site.

Detailed Summary

The goal of this clinical study is to learn about the effect of aging on certain enzymes, or proteins, in the blood and colon. The study involves collection of blood and colon tissue biopsies using a flexible sigmoidoscope or colonoscope. This study is also investigating how medications tenofovir and emtricitabine interact with certain enzymes. The investigators will compare the difference in enzyme activity between people taking tenofovir and emtricitabine, to those who are not taking tenofovir and emtricitabine.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infections, Aging
CountriesUnited States
CollaboratorsNational Institute of Allergy and Infectious Diseases (NIAID), National Institute on Aging (NIA)

Timeline

N/ACompletedFinished
202420252026
First PostedNov 15, 2023
Enrollment StartAug 7, 2023
Primary CompletionMay 20, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 2.6 years ago

Interventions

biopsyother

colorectal biopsy for tissue acquisition