CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 832 enrolled
Drug / intervention
Intravenous thrombolysis plus tirofiban +1 moredrug
Likely dose
Intravenous thrombolysis plus tirofiban 0.4 μgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06134622
NCT06134622Phase 3Completed

Advancing Stroke Safety and Efficacy Through Early Tirofiban Administration After Intravenous Thrombolysis (ASSET-IT)

The First Affiliated Hospital of University of Science and Technology of China·interventional·Posted Nov 18, 2023·Updated May 4, 2025

In Brief

A Phase 3 clinical trial evaluating Intravenous thrombolysis plus tirofiban and Intravenous thrombolysis plus placebo for Acute Ischemic Stroke. Completed, enrolled 832 participants across 1 site.

Detailed Summary

To assess the efficacy and safety of tirofiban administration after intravenous thrombolysis for patients with AIS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedNov 18, 2023
Enrollment StartMar 14, 2024
Primary CompletionSep 25, 2024
Study CompletionDec 30, 2024
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 2.6 years ago

Interventions

Intravenous thrombolysis plus tirofibandrug

Patients randomized to the Tirofiban group will receive continuous intravenous infusion of tirofiban for 24 hours: initial infusion of 0.4 μg/kg/min for 30 minutes followed by a continuous infusion of 0.1 μg/kg/min for up to 23.5 hours. The tirofiban placebo will be infused in a similar fashion.

Intravenous thrombolysis plus placebodrug

placebo (saline)