CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
s.c 25 mg estradiol pelletdrug
Likely dose
s.c 25 mg estradiol pelletfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06136208
NCT06136208N/ACompleted
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Pharmacokinetic Aspects of 25-mg Estradiol Pellet in Climacteric Women Comprehensive Longitudinal Assessment of Release With Estradiol Pellet Analysis (CLARA Study)

Science Valley Research Institute·interventional·Posted Nov 18, 2023·Updated Sep 8, 2025

In Brief

A clinical study evaluating s.c 25 mg estradiol pellet for Climacteric Syndrome and 2 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

A single center, prospective, open-label clinical study will be conducted, to monitor serum concentration and pharmacokinetic profile after subcutaneous implantation of a 25mg-estradiol bioabsorbable implant in postmenopausal women.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsClimacteric Syndrome, Menopause, Hypoestrogenism
CountriesBrazil
CollaboratorsBiòs Farmacêutica

Timeline

N/ACompletedFinished
202420252026
First PostedNov 18, 2023
Enrollment StartDec 13, 2023
Primary CompletionOct 9, 2024
Study CompletionJul 30, 2025
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 2.6 years ago

Interventions

s.c 25 mg estradiol pelletdrug

Subcutaneous insertion of 25 mg estradiol pellet.