CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 89 enrolled
Drug / intervention
VGT-309drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06145048
NCT06145048Phase 2Completed

A Phase 2, Multi-center, Open-label Study to Evaluate the Safety and Efficacy of VGT-309, a Tumor-Targeted, Activatable Fluorescent Imaging Agent, in Subjects Undergoing Surgery for Cancer in the Lung

Vergent Bioscience, Inc.·interventional·Posted Nov 22, 2023·Updated May 13, 2026

In Brief

A Phase 2 clinical trial evaluating VGT-309 for Lung Cancer and Lung Metastases. Completed, enrolled 89 participants across 6 sites in 2 countries.

Detailed Summary

This is a Phase 2, multi-center, open-label study to evaluate the safety and efficacy of VGT-309, a tumor-targeted, activatable fluorescent imaging agent, in subjects undergoing surgery for proven or suspected cancer in the lung. Approximately 100 subjects will be enrolled to ensure at least 86 subjects are evaluable with the option to expand enrollment by protocol amendment if deemed necessary by the DSC to meet primary and/or secondary objectives.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, United States
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedNov 22, 2023
Enrollment StartOct 5, 2023
Primary CompletionOct 31, 2024
Study CompletionFeb 20, 2025
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 2.6 years ago

Interventions

VGT-309drug

Intravenous drug to be given over 15-20 minutes by syringe pump.