CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 8 enrolled
Drug / intervention
sacubitril/valsartandrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06149104
NCT06149104Phase 3Completed

A Multicenter, Open-label Study to Collect the Safety Information of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study

Novartis Pharmaceuticals·interventional·Posted Nov 28, 2023·Updated Oct 14, 2025

In Brief

A Phase 3 clinical trial evaluating sacubitril/valsartan for Heart Failure. Completed, enrolled 8 participants across 6 sites.

Detailed Summary

The purpose of this open-label study was to collect additional safety information of sacubitril/valsartan and to provide post-trial access to sacubitril/valsartan for the eligible Japanese patients who completed CLCZ696B2319E1(NCT03785405) study until marketed product of pediatric formulation, film-coated granules in capsule, is available in Japan.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
202420252026
First PostedNov 28, 2023
Enrollment StartDec 4, 2023
Primary CompletionAug 14, 2024
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 2.6 years ago

Interventions

sacubitril/valsartandrug

sacubiril/valsartan