CI

At a glance

ClinicalIndex Comparison Record
Phase 2Recruiting· 88 target
Drug / intervention
tests to determine HRD statusgenetic
Likely dose
Not stated in record
Key inclusion· 8
  • Age 18 years or older
  • Histologically confirmed high-grade serous epithelial ovarian cancer, fallopian tube cancer, or peritoneal cancer
  • Newly diagnosed advanced disease (FIGO stage III or IV)
  • Candidate for first-line platinum-based chemotherapy
Key exclusion· 5
  • Recurrent high-grade serous epithelial ovarian, fallopian tube, or peritoneal cancer
  • Non-epithelial or borderline ovarian cancer
  • Other active tumor that may interfere with ovarian cancer treatment or significantly impact prognosis
  • Exclusive palliative setting

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06152731
NCT06152731Phase 2RecruitingHigh MomentumUpdated 9mo ago

HRD Tests for Ovarian cancER

Centre Francois Baclesse·interventional·Posted Dec 1, 2023·Updated Sep 17, 2025

In Brief

A Phase 2 clinical trial evaluating tests to determine HRD status for Ovarian Cancer. Currently recruiting, targeting 88 participants across 4 sites.

Signals

Enrolling ahead of pace

Detailed Summary

The study concerns patients with Invasive epithelial ovarian cancer, primary Fallopian tube carcinoma, ovarian-type peritoneal carcinoma, and with an indication of a first-line platinum-based chemotherapy. To determine HRD status, 2 separate tests will be performed in the study: 1. Giscar assay : developed by the sponsor 2. myChoice assay If one or two tests identifies a HRD status : a PARP inhibitor treatment may be initiated according to current recommendations

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOvarian Cancer
CountriesFrance
Collaborators--

Timeline

Phase 2Recruiting
20242025202620272028202920302031
First PostedDec 1, 2023
Enrollment StartFeb 15, 2024
Primary CompletionJun 1, 2031
TodayJul 2, 2026
Enrollment to primary: 7.3 yearsPosted 2.6 years agoPrimary completion in 4.9 years

Interventions

tests to determine HRD statusgenetic

Test Giscar AND test myChoice will be performed. If one or two tests identifies a HRD status : a PARP inhibitor treatment may be initiated according to current recommendations