CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 498 enrolled
Drug / intervention
Baloxavir Marboxildrug
Likely dose
Baloxavir Marboxil 40 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06161454
NCT06161454Phase 4Completed

A Feasibility Study of Xofluza Treatment of Influenza in Pediatric Transplant Recipients, Waitlisted Subjects and Household Members After Early Infection Alerting Using Wearable Devices

Children's Hospital of Philadelphia·interventional·Posted Dec 8, 2023·Updated Jul 11, 2025

In Brief

A Phase 4 clinical trial evaluating Baloxavir Marboxil for Infection, Coronavirus and 4 related conditions. Completed, enrolled 498 participants across 1 site.

Detailed Summary

The goal of this prospective, interventional, single-center study is to assess whether the early detection of Influenza with smart wearable device algorithms and alerting, rapid testing, and subsequent Baloxavir treatment demonstrate better post-infection outcomes versus publicly available- and Centers for Disease Control (CDC)-derived national statistics for equivalent household populations as well as pediatric kidney, heart, liver, lung transplant recipients and waitlisted patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsGenentech, Inc.

Timeline

Phase 4CompletedFinished
202420252026
First PostedDec 8, 2023
Enrollment StartDec 14, 2023
Primary CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 2.6 years ago

Interventions

Baloxavir Marboxildrug

Baloxavir marboxil will be administered as either a tablet or granules. Dose is based on body weight: 40 mg for a participants weighing 20-79 kg, or 80 mg for a patient weighing more than or equal to 80 kg