CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 172 enrolled
Drug / intervention
Vapocoolent +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06182631
NCT06182631Phase 3Completed
CompareCT.gov

A Randomized Clinical Trial of Buzzy Versus Vapocoolant in Pain Relief During Phlebotomy and IV Catheterization in the Pediatric ED

State University of New York at Buffalo·interventional·Posted Dec 27, 2023·Updated Oct 2, 2025

In Brief

A Phase 3 clinical trial evaluating Buzzy Bee, Vapocoolent, and 1 other intervention for Intravenous Administration. Completed, enrolled 172 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the anxiety and pain levels of patients when using Buzzy with ice, Vapocoolant, and placebo when inserting IV's line for IV fluids and/or phlebotomy in pediatric patients in the pediatric emergency department.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntravenous Administration
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedDec 27, 2023
Enrollment StartJul 15, 2019
Primary CompletionJan 15, 2021
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 2.5 years ago

Interventions

Buzzy Beedevice

The Buzzy is a vibrating palm-sized device with removable ice wings developed by MMJ Labs Atlanta, GA. It uses Melzack and Wall's Gait Control theorywhich asserts that activation of non-nociceptive fibers can interfere with signals from pain fibers thereby inhibiting pain.

Vapocoolentdrug

Vapocoolent is a volatile refrigerated liquid, ie ethyl chloride, which is supposed to feel like the skin is numb before insertion of the IV.

Placeboother

A band will be placed on the arm before IV insertion for placebo effect.