CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
IRE Systemdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06187194
NCT06187194N/ACompleted
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Evaluation of the Efficacy and Safety of an Irreversible Electroporation (IRE) System for Tonsil Reduction for The Treatment of Chronic Symptomatic Tonsillar Hypertrophy

ENTire Medical Ltd.·interventional·Posted Jan 2, 2024·Updated Apr 29, 2026

In Brief

A clinical study evaluating IRE System for Tonsillar Hypertrophy. Completed, enrolled 24 participants across 1 site.

Detailed Summary

The purpose of the IRE System is to address the clinical need for reducing the volume of chronic symptomatic hypertrophic tonsil(s) while minimizing side effects and complications. Procedure time will also be reduced. The IRE System is designed to be more comfortable for patients, as it employs a noninvasive procedure using a high voltage pulsed electric field to create irreversible nanopores in the cell membrane, leading to cell death and the reduction of tonsil volume.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTonsillar Hypertrophy
CountriesRomania
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedJan 2, 2024
Enrollment StartJan 17, 2024
Primary CompletionNov 15, 2024
Study CompletionFeb 2, 2025
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 2.5 years ago

Interventions

IRE Systemdevice

Irreversible Electroporation (IRE) System for Tonsil Reduction for the Treatment of Chronic Symptomatic Tonsillar Hypertrophy