CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 105 enrolled
Drug / intervention
Dexamethasone sodium phosphate +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06193200
NCT06193200Phase 3Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Neurological Effects of EryDex on Subjects With Ataxia Telangiectasia (NEAT)

Quince Therapeutics S.p.A.·interventional·Posted Jan 5, 2024·Updated Apr 30, 2026

In Brief

A Phase 3 clinical trial evaluating Dexamethasone sodium phosphate and Placebo for Ataxia Telangiectasia. Completed, enrolled 105 participants across 19 sites in 9 countries.

Detailed Summary

This is an international, multi-center, randomized, prospective, double-blind, placebo-controlled, Phase 3 study, designed to assess the effect of EryDex (dexamethasone sodium phosphate \[DSP\] in autologous erythrocytes), administered by intravenous (IV) infusion once every 28 days, on neurological symptoms of patients with Ataxia Telangiectasia (A-T).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesDenmark, Germany, Italy, Norway, Poland, Spain, Switzerland, United Kingdom, United States
CollaboratorsBiotrial

Timeline

Phase 3CompletedFinished
202420252026
First PostedJan 5, 2024
Enrollment StartJun 24, 2024
Primary CompletionDec 17, 2025
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 2.5 years ago

Interventions

Dexamethasone sodium phosphatedrug

Dexamethasone sodium phosphate encapsulated in autologous erythrocytes and administered via IV infusion

Placeboother

Placebo encapsulated in autologous erythrocytes and administered via IV infusion