CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
To evaluate the effectiveness and safety of a pharmacist-driven protocol to discontinue stress ulcer prophylaxis in ICU patients when it is no longer indicated according to pre-defined criteria.behavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06225167
NCT06225167N/ACompleted
CompareCT.gov

Pharmacist-Driven Stress Ulcer Prophylaxis Minimization in the Intensive Care Unit

Methodist Health System·observational·Posted Jan 25, 2024·Updated Mar 23, 2026

In Brief

An observational study evaluating To evaluate the effectiveness and safety of a pharmacist-driven protocol to discontinue stress ulcer prophylaxis in ICU patients when it is no longer indicated according to pre-defined criteria. for Stress Ulcer. Completed, enrolled 120 participants across 1 site.

Detailed Summary

Pharmacologic stress ulcer prophylaxis is routinely used in the intensive care unit (ICU) to prevent upper gastrointestinal (GI) bleeding in critically ill patients.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsStress Ulcer
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedJan 25, 2024
Enrollment StartMay 13, 2023
Primary CompletionJul 17, 2023
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 2.4 years ago

Interventions

To evaluate the effectiveness and safety of a pharmacist-driven protocol to discontinue stress ulcer prophylaxis in ICU patients when it is no longer indicated according to pre-defined criteria.behavioral

To evaluate the effectiveness and safety of a pharmacist-driven protocol to discontinue stress ulcer prophylaxis in ICU patients when it is no longer indicated according to pre-defined criteria. To compare the incidence of overt GI bleeds (defined as hematemesis, bloody nasogastric tube aspirate, or melena) between patients who were on stress ulcer prophylaxis versus patients whose acid suppression therapy was discontinued through the stress ulcer prophylaxis minimization protocol.