CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 98 enrolled
Drug / intervention
Num Vapocoolant Spray +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06227052
NCT06227052Phase 4Completed

Vapocoolant Application for Pain Reduction During Office-based Gynecologic Procedures: a Randomized Controlled Trial (VAPOR)

Queen's Medical Center·interventional·Posted Jan 26, 2024·Updated Sep 25, 2025

In Brief

A Phase 4 clinical trial evaluating Num Vapocoolant Spray and Placebo for Pain With Paracervical Block and 2 related conditions. Completed, enrolled 98 participants across 1 site.

Detailed Summary

The purpose of this study is to assess if Num vapocoolant spray decreases pain associated with paracervical block in gynecology procedures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
202420252026
First PostedJan 26, 2024
Enrollment StartFeb 5, 2024
Primary CompletionMar 7, 2025
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 2.4 years ago

Interventions

Num Vapocoolant Spraydevice

This is the study arm. Partipants in this arm will receive Num vapocoolant spray during their gynecologic procedure. They will receive the spray on their cervix right before the paracervical block. Num Vapocoolant spray is currently FDA approved to be used on skin prior to injections. The investigators are using it in the same fashion but in the vagina on the cervix to help with the pain of the paracervical block injection.

Placeboother

This is the placebo. This group will receive Natures tear normal saline spray.