At a glance
ClinicalIndex Comparison RecordN/ACompleted· 156 enrolled
Drug / intervention
The respiratory effort parameters guide sedative dosage.other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)
In Brief
A clinical study evaluating The respiratory effort parameters guide sedative dosage. for ARDS and 3 related conditions. Completed, enrolled 156 participants across 1 site.
Detailed Summary
The objective of this research is to utilize respiratory effort parameters as a tool to assist in adjusting sedative drug levels for patients undergoing mechanical ventilation in the intensive care unit, in comparison to the conventional usual care approach.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesThailand
Collaborators--
Timeline
N/ACompletedFinished
202420252026
Enrollment StartOct 2023
First PostedFeb 2024
Primary CompletionOct 2024
Study CompletionJun 2025
TodayJul 2026
First PostedFeb 5, 2024
Enrollment StartOct 1, 2023
Primary CompletionOct 31, 2024
Study CompletionJun 30, 2025
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 2.4 years ago
Interventions
The respiratory effort parameters guide sedative dosage.other
The intervention involves the measurement of respiratory effort using P0.1 and Pocc then calculating to dynamic transpulmonary pressure swing (Predicted ΔPL) to adjust sedative drug dosage.