CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 33 enrolled
Drug / intervention
Experimental Dentifrice +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06242444
NCT06242444N/ACompleted

A Randomized, Examiner Blind, Crossover, in Situ Erosion Study To Investigate The Efficacy Of An Experimental Dentifrice In Remineralization Of Softened Enamel Compared To Placebo and Reference Dentifrices

HALEON·interventional·Posted Feb 5, 2024·Updated May 8, 2025

In Brief

A clinical study evaluating Experimental Dentifrice, Placebo Control Dentifrice, and 1 other intervention for Tooth Erosion. Completed, enrolled 33 participants across 1 site.

Detailed Summary

The purpose of this study is to investigate the ability of an experimental dentifrice containing 1150 parts per million (ppm) fluoride to remineralize acid-softened dental enamel and help prevent further demineralization compared to a 0 ppm fluoride placebo dentifrice and a marketed, fluoride-containing dentifrice (Reference Dentifrice).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTooth Erosion
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 5, 2024
Enrollment StartFeb 26, 2024
Primary CompletionMay 7, 2024
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 2.4 years ago

Interventions

Experimental Dentifricedrug

Dentifrice containing 1150 ppm fluoride and 5% KNO3.

Placebo Control Dentifricedrug

Dentifrice containing 0 ppm fluoride and 5% KNO3.

Reference Dentifricedrug

Dentifrice containing 1100 ppm fluoride as SnF2.