CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled / 10 target
Drug / intervention
Behavioral Activation (BA) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06249386
NCT06249386N/ACompletedOn Track (0.6/mo)Completion was 8mo ago

Adapting and Piloting Behavioral Activation for Veterans With Co-Occurring AUD and Posttraumatic Stress Disorder

RTI International·interventional·Posted Feb 8, 2024·Updated Jun 9, 2026

In Brief

A clinical study evaluating Behavioral Activation (BA) and Relapse Prevention (RP) for Alcohol Use Disorder and Posttraumatic Stress Disorder. Completed, enrolled 10 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to compare an adaptation of Behavioral Activation, a behavioral intervention, to Relapse Prevention treatment, another behavioral intervention, in a sample of U.S. military veterans with co-occurring alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD). The primary aims of this study are to: 1. Adapt Behavioral Activation to treat veterans with AUD/PTSD, 2. Evaluate the feasibility, acceptability, and preliminary effects of Behavioral Activation for AUD/PTSD, and 3. Explore geospatial analysis as a new method for measuring AUD/PTSD recovery. Participants will complete self-report and interview measures immediately before and immediately after treatment. Participants will also be asked to participate in passive geospatial assessment for 14-day periods immediately before and immediately after treatment. Participants will be randomized to treatment condition, which involves 8 sessions of either Behavioral Activation or Relapse Prevention, delivered individually by a trained study therapist.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 8, 2024
Enrollment StartJan 17, 2025
Primary CompletionOct 6, 2025
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 2.4 years ago

Arms & Interventions

Behavioral Activation (BA)experimental

Individual psychotherapy

Behavioral: Behavioral Activation (BA)
Relapse Prevention (RP)active_comparator

Individual psychotherapy

Behavioral: Relapse Prevention (RP)

Interventions

Behavioral Activation (BA)behavioral

BA reduces alcohol use and posttraumatic stress symptoms and increases psychosocial functioning via psychoeducation, activity monitoring, values clarification, and activity scheduling.

Relapse Prevention (RP)behavioral

RP reduces alcohol use via increasing awareness and avoidance of high-risk situations, enhancing drink refusal skills, improving assertiveness, and other strategies.