CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 59 enrolled
Drug / intervention
CLE-400 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06262607
NCT06262607Phase 2Completed

A Randomized, Double-blind, Vehicle-controlled, Multicenter, Parallel-Design, Phase 2 Study to Assess the Efficacy and Safety of CLE-400 Topical Gel for the Treatment of Chronic Pruritus in Adult Subjects With Notalgia Paresthetica

Clexio Biosciences Ltd.·interventional·Posted Feb 16, 2024·Updated Nov 18, 2025

In Brief

A Phase 2 clinical trial evaluating CLE-400 and Vehicle for Chronic Pruritus in Adult Subjects With Notalgia Paresthetica (NP). Completed, enrolled 59 participants across 13 sites.

Detailed Summary

This is a Phase 2, randomized, double-blind, vehicle-controlled study to assess the efficacy and safety of CLE-400 topical gel for the treatment of chronic pruritus in adult subjects with Notalgia Paresthetica (NP).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedFeb 16, 2024
Enrollment StartJan 29, 2024
Primary CompletionNov 6, 2024
Study CompletionNov 19, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 2.4 years ago

Interventions

CLE-400drug

Topical CLE400 gel 0.28% administered once daily

Vehicledrug

Topical vehicle gel administered once daily