At a glance
ClinicalIndex Comparison RecordN/ACompleted· 90 enrolled
Drug / intervention
Esmolol +1 moredrug
Likely dose
Esmolol 1 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial Craniotomy
In Brief
A clinical study evaluating Scalp block and Esmolol for Hemodynamic Instability. Completed, enrolled 90 participants across 1 site.
Detailed Summary
The goal of this clinical trial is to compare hemodynamic response (MAP, SBP, DBP and HR) between scalp block and intravenous esmolol while skull pins application in patients undergoing elective supratentorial craniotomy under general anesthesia.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHemodynamic Instability
CountriesThailand
Collaborators--
Timeline
N/ACompletedFinished
2023202420252026
Enrollment StartSep 2022
Primary CompletionFeb 2024
Study CompletionFeb 2024
First PostedFeb 2024
TodayJul 2026
First PostedFeb 20, 2024
Enrollment StartSep 19, 2022
Primary CompletionFeb 1, 2024
Study CompletionFeb 13, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 2.4 years ago
Interventions
Scalp blockprocedure
Receive 30 ml of 0.25% bupivacaine with 1% lidocaine (1:1) with adrenaline 1:200,000 infiltration for 10 minutes before skull pins application.
Esmololdrug
Receive Intravenous esmolol 1 mg/kg bolus over 1 minute before skull pins application