CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 34 enrolled
Drug / intervention
Elpipodect +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06273774
NCT06273774Phase 1Completed

A Multiple Dose Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MK-8189 in Participants With Bipolar I Disorder

Merck Sharp & Dohme LLC·interventional·Posted Feb 23, 2024·Updated Apr 29, 2026

In Brief

A Phase 1 clinical trial evaluating Elpipodect and Placebo for Bipolar I Disorder. Completed, enrolled 34 participants across 3 sites.

Detailed Summary

The goal of this study is to evaluate the safety and tolerability of elpipodect in participants with stable bipolar I disorder. There was no hypothesis testing in this study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
20252026
First PostedFeb 23, 2024
Enrollment StartApr 8, 2024
Primary CompletionAug 21, 2024
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 2.4 years ago

Interventions

Elpipodectdrug

Oral Tablet

Placebodrug

Oral Tablet