CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 511 enrolled
Drug / intervention
Kit Buccal swab collection & stabilization de Canvax® +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06275243
NCT06275243N/ACompleted

Alzheimer's Disease as a Sociosanitary Priority: ApoE Gene Polymorphism

Universidad de León·interventional·Posted Feb 23, 2024·Updated May 8, 2024

In Brief

A clinical study evaluating Kit Buccal swab collection & stabilization de Canvax®, Cholesterol levels according to ApoE Genotype, and 1 other intervention for Alzheimer Disease. Completed, enrolled 511 participants across 1 site.

Detailed Summary

The general objective of this randomized and longitudinal clinical study was to estimate the frequencies of ApoE variants both in the user population of the "Messengers of Peace" Residences and the "Associations of Relatives of Alzheimer's Patients" in Castile y Leon, since, due to its geographical location at the crossroads, it has received multiple genetic contributions from both northern Europe, the Mediterranean area and northern Africa. The main questions it aims to answer are: * What are the allelic frequencies of ApoE variants in the population of individuals with Alzheimer's disease in Castile and Leon? * Is there a correlation between the ApoE4 variant and the lipid profile in the blood of individuals with Alzheimer's disease in this region?

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSpain

Timeline

N/ACompletedFinished
2023202420252026
First PostedFeb 23, 2024
Enrollment StartJul 6, 2022
Primary CompletionMar 13, 2023
Study CompletionMar 22, 2024
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 2.4 years ago

Interventions

Kit Buccal swab collection & stabilization de Canvax®other

Assessment of ApoE variant in saliva samples as a potential biomarker for Alzheimer's disease.

Cholesterol levels according to ApoE Genotypeother

Enhancing the quality of life of study participants by investigating cholesterol levels based on their ApoE genotype.

Assessing cardiovascular risk factors in all participantsother

Through individual interviews, record cardiovascular factors and assess their correlation with Alzheimer's disease.