CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 130 enrolled
Drug / intervention
Intra-articular infiltration of PVP Collagen +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06275880
NCT06275880N/ACompleted

Effectiveness of Intra-articular Collagen Polyvinylpyrrolidone in Patients With Symptomatic Gonarthross Attended in Rehabilitation of an IMSS-Yucatán Hospital.

Instituto Mexicano del Seguro Social·interventional·Posted Feb 23, 2024·Updated Feb 23, 2024

In Brief

A clinical study evaluating Intra-articular infiltration of PVP Collagen and Rehabilitation for Gonarthrosis. Completed, enrolled 130 participants across 1 site.

Detailed Summary

The objective of this clinical trial is to verify the effectiveness of polyvinyl pyrrolidone collagen in all patients with symptomatic gonarthrosis grades II-IV in patients over 40 years of age. The main objectives that this study aims to answer are the following: 1. \- Document the effectiveness of intra-articular polyvinylpyrrolidone collagen in the treatment of symptomatic gonarthrosis. 2. \- Compare the intensity of pain, the degree of stiffness and functionality of the joint, prior to application and one month after the therapeutic intervention. 3. \- Identify demographic, clinical and therapeutic factors that influence the effectiveness of intra-articular PVP collagen in the treatment of symptomatic gonarthrosis. Patients diagnosed with symptomatic gonarthrosis Grade II-IV, referred to the Physical Medicine and Rehabilitation service within 3 months, will be selected. Two study groups will be assigned: GROUP those who received intra-articular infiltration of PVP Collagen, GROUP B: patients who received conservative treatment. Through rehabilitation with a home program for one month, in both cases, ENA and the WOMAC scale will be evaluated at the beginning of the study and after 4 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGonarthrosis
CountriesMexico
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedFeb 23, 2024
Enrollment StartApr 1, 2023
Primary CompletionJul 30, 2023
Study CompletionJan 10, 2024
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 2.4 years ago

Interventions

Intra-articular infiltration of PVP Collagenother

Intra-articular collagen injection plus physiotherapy program

Rehabilitationother

Patients who received conservative treatment through rehabilitation with a home program for one month