CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 133 enrolled
Drug / intervention
DMB-I (Dimebon) +1 moredrug
Likely dose
DMB-I (Dimebon) 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06292351
NCT06292351Phase 2Completed

Multicenter Randomized Double-blind Placebo-controlled Three-arm Parallel-group Clinical Study to Evaluate the Efficacy and Safety of DMB-I in the Treatment of Dementia Associated With Alzheimer's Disease

Bigespas LTD·interventional·Posted Mar 5, 2024·Updated Mar 28, 2025

In Brief

A Phase 2 clinical trial evaluating DMB-I (Dimebon) and Placebo for Alzheimer Disease and Dementia of Alzheimer Type. Completed, enrolled 133 participants across 7 sites.

Detailed Summary

The purpose of this study is to assess the efficacy and safety of DMB-I for the treatment of patients with Alzheimer type dementia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesRussia
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedMar 5, 2024
Enrollment StartDec 27, 2023
Primary CompletionJan 13, 2025
Study CompletionJan 31, 2025
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 2.3 years ago

Interventions

DMB-I (Dimebon)drug

20 mg 3 times a day, or 10 mg + 10 mg 3 times a day (for DMB-I + Placebo arm)

Placeboother

20 mg 3 times a day, or 10 mg + 10 mg 3 times a day (for DMB-I + Placebo arm)