At a glance
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Efficacy of Combination of Hdroxyurea and Thalidomide Over Either Hydroxyurea or Thalidomide Alone in the Treatment of Transfusion Dependent Thalassemia in Children: A Quasi-Randomised Clinical Trial
In Brief
A Phase 4 clinical trial evaluating Thalidomide, Hydroxy Urea, and 1 other intervention for Transfusion-dependent Thalassemia. Completed, enrolled 90 participants across 1 site.
Signals
Detailed Summary
The goal of this clinical trial is to find out the efficacy of combined Hydroxyurea and thalidomide transfusion dependent thalassemia patients. The main objectives are to compare the level of Hb, Transfusion interval, serum ferritin level before \& after treatment between single and combination of thalidomide and HU. Researcher will compare the effectiveness of combined hydroxyurea and thalidomide and hydroxyurea and thalidomide alone. Participants will be divided in three groups: Group I: will take combination of HU and Thalidomide. Group II: Will take HU alone and Group III: Will take Thalidomide alone and outcome will be recorded.
Study Details
Timeline
Arms & Interventions
Patient getting Thalidomide
Hydroxyurea
combination of Thalidomide \& Hydroxyurea
Interventions
Patients will get only Thalidomide
Patients will get only Hydroxyurea
Combination Of Thalidomide \& Hydroxyurea