CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 46 enrolled
Drug / intervention
GM-1020drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06309277
NCT06309277Phase 2Completed

A Two-Part Controlled Clinical Study to Evaluate Safety, Tolerability, Response, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Doses of GM-1020 in Patients With Major Depressive Disorder

Gilgamesh Pharmaceuticals·interventional·Posted Mar 13, 2024·Updated May 8, 2026

In Brief

A Phase 2 clinical trial evaluating GM-1020 for Major Depressive Disorder. Completed, enrolled 46 participants across 1 site.

Detailed Summary

The aim of this Phase 2a study in patients with MDD is to assess safety and tolerability and preliminary antidepressant efficacy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedMar 13, 2024
Enrollment StartFeb 1, 2024
Primary CompletionMar 4, 2025
Study CompletionMar 27, 2025
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 2.3 years ago

Interventions

GM-1020drug

N-methyl-D-aspartate (NMDA) receptor antagonist