CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
one trocar-assisted retroperitoneoscopic ureteroureterostomy (OTAU)procedure
Likely dose
Not stated in record
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Search/NCT06350942
NCT06350942N/ACompleted

One Trocar-assisted Retroperitoneoscopic Ureteroureterostomy for Ureteral Duplication

National Children's Hospital, Vietnam·observational·Posted Apr 8, 2024·Updated Apr 8, 2024

In Brief

An observational study evaluating one trocar-assisted retroperitoneoscopic ureteroureterostomy (OTAU) for Ureteral Duplication. Completed, enrolled 40 participants across 2 sites.

Detailed Summary

Ureteral duplication, a common anomaly affecting about 0.8% of the population, presents challenges in pediatric urology due to its diverse clinical presentations and anatomical complexity. Traditional treatments like upper pole moiety (UPM) heminephrectomy can lead to loss of renal function in the remaining lower pole moiety (LPM). Ureteroureterostomy (UU) is a safer alternative, increasingly preferred regardless of renal function or reflux presence. Minimally invasive techniques like laparoscopic and robotic procedures show promise, but robotic-assisted UU is costly, while laparoscopic UU has technical challenges. A novel approach is proposed: single-trocar retroperitoneoscopic-assisted UU, combining laparoscopic visualization advantages with simplified extracorporeal suturing, offering a promising solution for managing complete ureteral duplication. The present study was designed to describe the operative technique and outcome of OTAU in 40 cases of complete ureteral duplication in children.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesVietnam

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedApr 8, 2024
Enrollment StartSep 1, 2016
Primary CompletionDec 1, 2020
Study CompletionFeb 1, 2024
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 2.2 years ago

Interventions

one trocar-assisted retroperitoneoscopic ureteroureterostomy (OTAU)procedure

A 12 mm transverse incision was made just above the iliac crest, followed by careful dissection of the fascia and muscle layer to expose the Gerota's fascia. Entry into the retroperitoneal space was achieved with a 10-mm balloon trocar, allowing for pneumoretroperitoneum establishment. Using a 10-mm laparoscope equipped with a Maryland dissector, the ureters were dissected and isolated, followed by careful exteriorization of both upper and lower pole moiety ureters with a Babcock grasper. The pathological upper pole moiety ureter was transected, preserving the normal lower pole moiety ureter and shared blood supply, and closed with a Vicryl 4/0 suture. Subsequently, an end-to-side ureteroureterostomy was performed with a 6/0 Polydioxanone running suture, with antegrade insertion of a double J stent if not previously conducted. A final retroperitoneoscopic evaluation ensured proper anastomosis alignment, and the incision was closed without drainage.