CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 331 enrolled / 331 target
Drug / intervention
cobas® liat CT/NG/MG nucleic acid test +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06369220
NCT06369220N/ACompletedHigh Momentum (14.3/mo)Completion was 13mo ago

A Study of the Clinical Utility of Point of Care Cobas® Liat CT/NG/MG Nucleic Acid Test Versus Current Standard Practice

Hoffmann-La Roche·interventional·Posted Apr 16, 2024·Updated Jun 23, 2026

In Brief

A clinical study evaluating cobas® liat CT/NG/MG nucleic acid test and Standard of Care (SOC): Clinician's Standard Practice for Chlamydia Trachomatis Infection and 2 related conditions. Completed, enrolled 331 participants across 4 sites.

Signals

Enrolling ahead of pace

Detailed Summary

This study is designed to assess the comparative clinical utility of the point of care cobas® liat CT/NG/MG to current standard practices in the diagnosis and treatment of urogenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20252026
First PostedApr 16, 2024
Enrollment StartJul 29, 2024
Primary CompletionMay 28, 2025
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 2.2 years ago

Arms & Interventions

Standard of Care (SOC) Arm: Standard Practiceother

In the SOC arm, the clinician will evaluate the participant based on standard practice.

Other: Standard of Care (SOC): Clinician's Standard Practice
Point of Care (POC) Arm: cobas® liat CT/NG/MGexperimental

In the POC arm, the clinician will evaluate the participant and will be provided POC test results upon which they may choose to base their clinical decisions.

Diagnostic Test: cobas® liat CT/NG/MG nucleic acid test

Interventions

cobas® liat CT/NG/MG nucleic acid testother

The cobas® CT/NG/MG nucleic acid test for use on the cobas® Liat® System is an investigational, automated, qualitative in vitro nucleic acid diagnostic test that utilizes real-time polymerase chain reaction (PCR) for the direct detection of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) nucleic acid in male/female urine and vaginal swabs (clinician-collected and self-collected) in cobas® PCR Media.

Standard of Care (SOC): Clinician's Standard Practiceother

Standard of care (SOC) is defined as the traditional/typical diagnosis and treatment steps in practice recommended by the CDC guidelines that rely upon clinical syndromic presentations and/or external laboratory testing.