CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,459 enrolled
Drug / intervention
RSVPreF3 OA investigational vaccinebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06389487
NCT06389487Phase 3Completed

A Phase 3b, Open-label Study to Evaluate the Non-inferiority of the Immune Response and to Evaluate the Safety of the RSVPreF3 OA Investigational Vaccine in Adults 18-49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults >=60 Years of Age

GlaxoSmithKline·interventional·Posted Apr 29, 2024·Updated Sep 25, 2025

In Brief

A Phase 3 clinical trial evaluating RSVPreF3 OA investigational vaccine for Respiratory Syncytial Virus Infections. Completed, enrolled 1,459 participants across 52 sites in 6 countries.

Detailed Summary

The aim of this study is to demonstrate the immune response and to evaluate the safety of the RSVPreF3 OA investigational vaccine in non-immunocompromised adults 18-49 years of age (YOA), who are at increased risk (AIR) for RSV disease, compared to older adults (OA) 60 YOA and above.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Canada, Germany, Japan, South Africa, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20252026
First PostedApr 29, 2024
Enrollment StartApr 29, 2024
Primary CompletionJul 29, 2024
Study CompletionMar 18, 2025
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 2.2 years ago

Interventions

RSVPreF3 OA investigational vaccinebiological

1 dose of RSVPreF3 OA investigational vaccine is administered intramuscularly on Day 1.