CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 10 enrolled
Drug / intervention
Sunitinib +6 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06390826
NCT06390826Phase 2Active

MATCH Treatment Subprotocol V: Phase II Study of Sunitinib in Patients With Tumors With cKIT Mutations (Excluding GIST, Renal Cell Carcinoma or Pancreatic Neuorendocrine Tumor)

National Cancer Institute (NCI)·interventional·Posted Apr 30, 2024·Updated May 28, 2026

In Brief

A Phase 2 clinical trial evaluating Biopsy Procedure, Biospecimen Collection, and 5 other interventions for Advanced Lymphoma and 4 related conditions. Active but no longer recruiting, targeting 10 participants across 1 site.

Detailed Summary

This phase II MATCH treatment trial tests how well sunitinib in treating patients with cancer that has certain genetic changes. Sunitinib is in a class of medications called kinase inhibitors. It is used in patients whose cancer has a certain mutation (change) in the cKIT gene. It works by blocking the action of mutated cKIT that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
20172018201920202021202220232024202520262027
First PostedApr 30, 2024
Enrollment StartNov 1, 2016
Primary CompletionApr 5, 2023
Study CompletionJan 15, 2027
TodayJul 2, 2026
Enrollment to primary: 6.4 yearsPosted 2.2 years ago

Interventions

Biopsy Procedureprocedure

Undergo biopsy

Biospecimen Collectionprocedure

Undergo blood sample collection

Computed Tomographyprocedure

Undergo CT scan

Echocardiography Testprocedure

Undergo ECHO

Magnetic Resonance Imagingprocedure

Undergo MRI

Radionuclide Imagingprocedure

Undergo nuclear study

Sunitinibdrug

Given PO