At a glance
ClinicalIndex Comparison RecordPhase 3Active· 36 target
Drug / intervention
estriol creamdrug
Likely dose
estriol cream 1 gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
NCT06391372Phase 3ActiveUpdate OverdueUpdated 16mo ago · Completion was 16mo agoEnrollment Stalled
Effect of Local Estriol Treatment Before Vaginal Repair Surgery on Vaginal Tissues and Early Postoperative Pelvic Floor Functions
In Brief
A Phase 3 clinical trial evaluating estriol cream for Pelvic Organ Prolapse and 3 related conditions. Active but no longer recruiting, targeting 36 participants across 1 site.
Signals
Enrollment appears stalled
Detailed Summary
The aim of the study is to evaluate the effects of local estriol treatment applied before vaginal repair surgery on steroid receptors, inflammatory cell response, vascular, connective and nervous tissues in the vagina, and its effects on early postoperative period pelvic floor functions, satisfaction with the surgery and vaginal health.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--
Timeline
Phase 3ActiveOverdue
20252026
Enrollment StartApr 2024
First PostedApr 2024
Primary CompletionMar 2025
TodayJul 2026
First PostedApr 30, 2024
Enrollment StartApr 1, 2024
Primary CompletionMar 1, 2025
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 2.2 years ago
Interventions
estriol creamdrug
1 g intravaginal estriol via applicator twice a week before going to bed for 4 weeks