CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 64 enrolled
Drug / intervention
Nerandomilast +1 moredrug
Likely dose
Nerandomilast 240 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06393127
NCT06393127Phase 1Completed

Bioequivalence of the BI 1015550 High Dose Formulation C2 and the BI 1015550 High Dose Formulation C1 (Phase 3 Formulation) Following Oral Administration in Healthy Subjects (an Open-label, Randomised, Single-dose, Two-way Crossover Trial)

Boehringer Ingelheim·interventional·Posted May 1, 2024·Updated Dec 1, 2025

In Brief

A Phase 1 clinical trial evaluating Nerandomilast for Healthy. Completed, enrolled 64 participants across 1 site.

Detailed Summary

The main objective of this trial is to establish the bioequivalence of the BI 1015550 Formulation C2 (Test, T) and the BI 1015550 Formulation C1 (Reference, R), following a single oral dose administration.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
20252026
First PostedMay 1, 2024
Enrollment StartJun 4, 2024
Primary CompletionSep 10, 2024
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 2.2 years ago

Interventions

Nerandomilastdrug

One dose of Formulation C2 (Test treatment - T) administered with approximately 240 mL of water after an overnight fast of at least 10 h. After drug administration, subjects additionally fasted for 4 h.

Nerandomilastdrug

One dose of Formulation C1 - phase 3 formulation (Reference treatment - R) administered with approximately 240 mL of water after an overnight fast of at least 10 h. After drug administration, subjects additionally fasted for 4 h.