At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparing Sulfur to Different Regimes of Permethrin for the Treatment of Scabies
In Brief
A Phase 3 clinical trial evaluating Permethrin Solution and Sulfur for Scabies. Completed, enrolled 250 participants across 3 sites.
Detailed Summary
In 2017, the World Health Organization (WHO) labeled scabies as a neglected tropical disease. It is a serious health problem especially in poor developing countries like Syria, where overcrowding, poverty, and war consequences are considered major factors for spreading the disease. Permethrin lotion or cream is the treatment of choice for scabies, and it is applied once a week for two consecutive weeks according to the global guidelines. However, most practitioners in Syria do not adhere to this standard regimen, and a variety of regimens are used instead based mostly on clinical experience. In this study, the investigators are comparing four different regimens of permethrin application and comparing Sulfur to permethrin in terms of efficacy and safety.
Study Details
Timeline
Interventions
permethrin 5 % solution
Sulfur 10%+ vaseline 90 % ointment