CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 146 enrolled / 146 target
Drug / intervention
Maternal Nutrition Education +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06397118
NCT06397118N/ACompletedHigh Momentum (7.4/mo)Completion was 3mo ago

Prevention of Malnutrition in Children With Sickle Cell Disease Living in Northern Nigeria

Vanderbilt University Medical Center·interventional·Posted May 2, 2024·Updated Jun 17, 2026

In Brief

A clinical study evaluating Maternal Nutrition Education and Standard Care for Sickle Cell Disease and Malnutrition. Completed, enrolled 146 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

The investigators are studying how to prevent malnutrition in children with sickle cell disease (SCD) in northern Nigeria. Community health workers will teach mothers about nutritious local foods that might help children grow better than the usual advice from doctors. The investigators will enroll 148 children with SCD aged 6 to 18 months old. The investigators will determine if their weight and diet improve and check for low vitamin A levels. This information will help us find better ways to improve growth for children with SCD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20252026
First PostedMay 2, 2024
Enrollment StartNov 6, 2024
Primary CompletionMar 12, 2026
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 2.2 years ago

Arms & Interventions

Standard Care plus Maternal Nutrition Educationexperimental

Mothers whose infants are assigned to this group will be provided individually by a community health worker during weeks 0, 8, and 16. In addition to receiving nutrition counseling, maternal nutrition education will emphasize utilizing locally available foods to enhance the nutritional well-being of young children and families, all while respecting local cultural and religious customs. To reinforce these educational messages, visual aids will be incorporated. The following educational messages will be addressed: 1. appropriate feeding frequency 2. dietary diversity using local foods 3. Complementary food preparation 4. adequate portions 5. individualized, tailored economic education regarding the cost of purchasing foods that can fill nutrient gaps (self-efficacy)

Behavioral: Maternal Nutrition EducationBehavioral: Standard Care
Standard Care Onlyactive_comparator

Mothers whose infants are assigned to the control group will receive standard nutrition education from the provider at the SCD clinic during weeks 0, 8, and 16.

Behavioral: Standard Care

Interventions

Maternal Nutrition Educationbehavioral

Community Health Worker delivered Maternal Nutrition Education

Standard Carebehavioral

Standard care in the sickle cell disease (SCD) clinic