CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 71 enrolled / 71 target
Drug / intervention
CPO Pro IOL +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06401551
NCT06401551N/ACompletedOn Track (2.9/mo)Completion was 18mo ago

Contralateral Study of Clareon PanOptix Pro vs. Clareon PanOptix

Alcon Research·interventional·Posted May 6, 2024·Updated Jun 2, 2026

In Brief

A clinical study evaluating CPO Pro IOL, CPO IOL, and 1 other intervention for Aphakia and Presbyopia. Completed, enrolled 71 participants across 8 sites.

Detailed Summary

The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAphakia, Presbyopia
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedMay 6, 2024
Enrollment StartJun 18, 2024
Primary CompletionDec 13, 2024
Study CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 2.2 years ago

Arms & Interventions

CPO Pro IOLexperimental

CPO Pro IOL implanted in the first eye, as randomized. The fellow eye will receive CPO IOL. The second eye surgery will occur approximately 7-14 days after the first eye surgery.

Device: CPO Pro IOLDevice: CPO IOLProcedure: Cataract Surgery
CPO IOLexperimental

CPO IOL implanted in the first eye, as randomized. The fellow eye will receive CPO Pro IOL. The second eye surgery will occur approximately 7-14 days after the first eye surgery.

Device: CPO Pro IOLDevice: CPO IOLProcedure: Cataract Surgery

Interventions

CPO Pro IOLdevice

Intraocular lens (IOL) implanted in the eye for the visual correction of aphakia in adult patients with less than 1 diopter of preexisting corneal astigmatism in whom a cataractous lens has been removed. The IOL is intended to mitigate the effects of presbyopia on intermediate and near visual acuity while maintaining comparable distance visual acuity. The Clareon™ PanOptix™ Pro Trifocal IOL is designed to enhance distance image quality by reducing chromatic aberration.

CPO IOLdevice

Intraocular lens (IOL) implanted in the eye for the visual correction of aphakia in adult patients with less than 1 diopter of preexisting corneal astigmatism in whom a cataractous lens has been removed. The IOL is intended to mitigate the effects of presbyopia on intermediate and near visual acuity while maintaining distance visual acuity.

Cataract Surgeryprocedure

Extraction of the cataractous lens by phacoemulsification, followed by implantation of the IOL