CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 174 enrolled
Drug / intervention
regional anesthesia and PAI +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06410612
NCT06410612Phase 4Completed

The Effect of Regional Anesthesia and Periarticular Injection and Versus Periarticular Injection Alone on Early Recovery After Total Knee Arthroplasty: A Prospective Randomized Trial

Washington University School of Medicine·interventional·Posted May 13, 2024·Updated Apr 20, 2026

In Brief

A Phase 4 clinical trial evaluating regional anesthesia and PAI and PAI for Pain, Postoperative. Completed, enrolled 174 participants across 1 site.

Detailed Summary

The purpose of the study is to compare two types of perioperative analgesic modalities, adductor canal block plus interspace between popliteal artery and capsule of the knee (IPACK) block and periarticular injection versus periarticular injection alone, to determine their relative efficacies with regard to pain relief and functional outcomes in the early postoperative period following primary total knee arthroplasty.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20252026
First PostedMay 13, 2024
Enrollment StartMar 4, 2024
Primary CompletionMay 12, 2025
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 2.1 years ago

Interventions

regional anesthesia and PAIdrug

this is the block portion of the study

PAIdrug

this is the no block portion of the study