CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 39 enrolled
Drug / intervention
Parental Support Cold Pressor Taskbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06445712
NCT06445712N/ACompleted

Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology

Washington University School of Medicine·interventional·Posted Jun 6, 2024·Updated Jan 27, 2026

In Brief

A clinical study evaluating Parental Support Cold Pressor Task for Child Development. Completed, enrolled 39 participants across 1 site.

Detailed Summary

The goal of this study is to investigate the role of physical pain in the link between childhood adversity and later psychopathology. Children who are participating in a larger longitudinal study will be asked to submerge their hand in cold water and hold it in the cold water as long as possible. Participants will do this twice, once alone and once holding the hand of their parent, to examine the role of parental support in pain development. The study will examine self-report of pain and salivary cortisol response to pain. It is hypothesized that children who have been exposed to more adversity will experience increased pain response and increased psychopathology symptoms. It is expected that higher social support in the family will decrease this relationship.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20252026
First PostedJun 6, 2024
Enrollment StartMay 1, 2024
Primary CompletionMar 23, 2025
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 2.1 years ago

Interventions

Parental Support Cold Pressor Taskbehavioral

Child will submerge their hand in cold water alone and holding the hand of a parent.