CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06456385
NCT06456385N/ACompleted

Investigate the Anti-pain Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Patients With Chronic Post-stroke Upper Extremity Pain

Medical University of South Carolina·interventional·Posted Jun 13, 2024·Updated Aug 22, 2025

In Brief

A clinical study evaluating Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) and Sham Auricular Stimulation for Stroke and Pain. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The purpose of this study is to explore whether a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) can change the way participants perceive pain. Investigators will recruit up to 20 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke, Pain
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedJun 13, 2024
Enrollment StartJun 4, 2024
Primary CompletionSep 26, 2024
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 2.1 years ago

Interventions

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)device

The intervention applied is called transcutaneous auricular vagus nerve stimulation (taVNS) which administers electrical stimulation at the ear which targets the auricular branch of the vagus nerve.

Sham Auricular Stimulationdevice

The sham auricular stimulation administers electrical stimulation at the ear lobe which has less auricular branch of the vagus nerve.