CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 92 enrolled
Drug / intervention
Nervio-Xdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06477276
NCT06477276N/ACompleted

A Multicenter, Randomized, Controlled, Double-Blind Trial on the Efficacy and Safety of Amygdala Temporal Interference Stimulation for the Treatment of Depression.

Ruijin Hospital·interventional·Posted Jun 27, 2024·Updated Jun 19, 2025

In Brief

A clinical study evaluating Nervio-X for Major Depressive Disorder. Completed, enrolled 92 participants across 3 sites.

Detailed Summary

The current investigation employs a directed neuromodulation technique, specifically targeting the right amygdala, to ascertain its therapeutic efficacy in managing depressive episodes. The intervention's safety and efficacy will be evaluated using an assessment incorporating depressive symptomatology, cognitive abilities, and daily functions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina

Timeline

N/ACompletedFinished
20252026
First PostedJun 27, 2024
Enrollment StartJul 24, 2024
Primary CompletionMay 1, 2025
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 2.0 years ago

Interventions

Nervio-Xdevice

An 8-channel TIS device developed by NEURODOME Corporation.