CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled / 100 target
Drug / intervention
Sequence of manual therapy techniques +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06477822
NCT06477822N/ACompletedOn Track (4.0/mo)Completion was 5mo ago

Effect of a Sequence of Specific Manual Therapy Techniques Targeting the Autonomic Nervous System in Healthy Adults: a Single-application Double-blind Randomized Controlled Trial

Universitat Internacional de Catalunya·interventional·Posted Jun 27, 2024·Updated Jun 30, 2026

In Brief

A clinical study evaluating Sequence of manual therapy techniques and Simulated manual therapy techniques for Autonomic Imbalance. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The activity of the autonomic nervous system has been shown to influence the appearance of symptoms in some diseases such as rheumatoid arthritis, fibromyalgia, or migraine, among others. In the bibliography we find different authors who, through intervention using manual therapy, have demonstrated its effects on the autonomic nervous system, especially on the increase in parasympathetic activity and reduction in sympathetic activity. A clinical trial is proposed to verify these effects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSpain
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedJun 27, 2024
Enrollment StartMay 23, 2024
Primary CompletionJan 30, 2026
Study CompletionFeb 13, 2026
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 2.0 years ago

Arms & Interventions

Sequence of manual therapy techniquesexperimental

Participants receive a manual therapy secuence of techniques

Procedure: Sequence of manual therapy techniques
Simulated manual therapy techniquesplacebo_comparator

Participants receive a sequence of simulated manual therapy techniques

Procedure: Simulated manual therapy techniques

Interventions

Sequence of manual therapy techniquesprocedure

Receive a sequence of manual therapy techniques composed by: suboccipital decompression technique, suboccipital release technique, fourth ventricle compression technique, vagus nerve neurodynamic technique

Simulated manual therapy techniquesprocedure

Receive a sequence of simulated manual therapy techniques composed by four maneuvers without effect on autonomic nervous system