CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 55 enrolled
Drug / intervention
Noribogainedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT06480981
NCT06480981Phase 1Completed

A Randomized, Double-blind, Placebo-controlled Trial to Evaluate Multiple Dose Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Ascending Doses of Noribogaine in Healthy Volunteers.

DemeRx NB·interventional·Posted Jul 1, 2024·Updated Jan 22, 2026

In Brief

A Phase 1 clinical trial evaluating Noribogaine for Pharmacokinetics. Completed, enrolled 55 participants across 1 site.

Detailed Summary

This trial will be a randomised, double-blind, sequential-group, multiple-dose, placebo-controlled, dose escalation trial to characterise the pharmacokinetics (PK), pharmacodynamics (PD) and safety of noribogaine in healthy adult participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 1CompletedFinished
20252026
First PostedJul 1, 2024
Enrollment StartJun 20, 2024
Primary CompletionDec 23, 2024
Study CompletionJan 13, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 2.0 years ago

Interventions

Noribogainedrug

Noribogaine capsules